The Clayton Lab resides within Allwine Hall at the University of Nebraska at Omaha. Our research is focused on understanding host-microbiome interactions in humans and nonhuman primates. We utilize both in vitro and in vivo systems, as well as a combination of next-generation sequencing, metabolomics, and bioinformatic approaches. We rely on the Nebraska Food for Health Center at the University of Nebraska-Lincoln for research-related resources, including the Gnotobiotic Mouse Program and the Food Processing Center. At UNO, we use common marmosets to study the effects of dysbiosis on the microbiota-gut-brain axis. Another area of research in the lab focuses on the effects of dietary variation and lifestyle factors on microbiome and metabolic health. The overarching goal of our research is to better human lives by gaining an understanding of how the microbiome can affect behavior and health.